QBI Neuroscience Seminar: Nuclear factor one transcription factors and cortical development
Event Details
- Date:
- Wednesday, 19 November 2014 - Wednesday, 19 November 2014
- Time:
- 12:00 pm - 1:00 pm
- Room:
- Auditorium, level 7
- UQ Location:
- Queensland Brain Institute (St Lucia)
- URL:
- http://www.qbi.uq.edu.au/neuroscience-seminars
- Event category(s):
Event Contact
- Name:
- Mr Reeza Nazer
- Phone:
- 66353
- Email:
- r.nazer@uq.edu.au
- Org. Unit:
- Queensland Brain Institute
Event Description
- Full Description:
- Speaker: Dr Michael Piper
Queensland Brain Institute, The University of Queensland
Title: Nuclear factor one transcription factors and cortical development
Abstract: My research interests lie within the field of developmental neurobiology. Specifically, the goal of my laboratory is to understand the cellular and molecular mechanisms that regulate how neural stem cells either self-renew or exit the cell cycle and differentiate into neurons or glia. We investigate this question using the mouse cerebral cortex as a model system, as this enables us to investigate the determinants of cortical development in a mammalian species that offers the prospect of knockout and transgenic strains. Given the immense complexity of the mammalian cerebral cortex, we believe that it is critical to gain a comprehensive understanding of the genes that control the genesis of this structure so as to inform our understanding of the large number of neurodevelopmental disorders that afflict our society. Moreover, the realisation that neural stem cells persist within the adult brain, and that decreases within this stem cell pool during stress, dementia and cognitive decline culminate in impaired brain function, highlights the critical need to understand the basic biology of these cells in far greater detail. Finally, the laboratory is also interested in applying our understanding of factors that drive neural stem cell differentiation into more translational and clinical realms, as we believe that our findings can successfully inform the study of disorders of aberrant stem cell division, including brain cancers such as glioma.
Directions to UQ
- Google Map:
-
- Directions:
- St Lucia Campus | Gatton campus.
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