QBI Neuroscience Seminar: 'Electrophysiological Analyses of Sleep States in Drosophila'
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- Dr Melvyn Yap
Queensland Brain Institute, University of Queensland
Title: 'Electrophysiological Analyses of Sleep States in Drosophila'
Abstract: Understanding the electrophysiological properties of the sleeping brain is an important step towards understanding sleep functions. Sleep studies in the fruit fly Drosophila melanogaster have begun to unravel molecular mechanisms involved in sleep regulations. However, the electrophysiological properties of sleep, a key component in mammalian sleep research, remain largely unexplored in fly sleep research. Here I will present my work in developing novel brain recording techniques for sleeping flies, using various methods of sleep induction techniques, discovering a distinct oscillatory brain activity that suggests a transitional sleep stage, and attempts at elucidating the role of this oscillatory activity. The results of these studies reveal that sleep in even the smallest brains is not a single, simple phenomenon, but rather involves distinct stages with likely different roles.
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