QBI Neuroscience Seminar: 'Understanding the role of microglia as regulators of adult neurogenesis in the intact and injured brain'
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- Dr Jana Vukovic
Queensland Brain Institute, University of Queensland and School of Biomedical Sciences, University of Queensland
Title: 'Understanding the role of microglia as regulators of adult neurogenesis in the intact and injured brain'
Abstract:
The hippocampus is one of the primary brain structures critical for learning and memory. The continuous and regulated production of new neurons – adult neurogenesis – in this part of the brain is believed to underpin some of the hippocampal-based cognitive functions. These newborn neurons are produced from a pool of neural precursor/stem cells, and we have previously shown that microglia play a key role in this process although the mechanisms behind this remain poorly understood. In this talk, I will present our most recent data on regulation of adult neurogenesis by microglia following traumatic brain injury, and the implications of this for behavioural outcomes.
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