AIBN Virtual Seminar Series: The Effects of Microgravity on Cellular and Disease Mechanotransduction
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- The Effects of Microgravity on Cellular and Disease Mechanotransduction Presented by Dr Joshua Chou, Senior Lecturer, School of Biomedical Engineering, University of Technology Sydney (UTS).
Register today to avoid missing your chance to tune in! Register here: https://uqz.zoom.us/webinar/register/WN_3qdsQLfEQ9aMz0bs6ZCPDg
Abstract: Deep space exploration is a new environment that humans could be exposed to in the future, where health risks associated with long-term exposure to microgravity needs to be assessed. The impact on the human physiology in particularly at the cellular level remains largely unknown. Cellular Mechanotransduction response in microgravity provides a unique insight into how cells and diseases respond to this new environment. This webinar will look at how simulated microgravity can help understand bone cells and cancer Mechanotransduction to identify new biomarkers and biological mechanisms. A greater understanding of cells and diseases in these extreme environments, may unlock new insights into the understanding of human diseases.
Dr. Joshua Chou is currently a Senior Lecturer in the School of Biomedical Engineering at the University of Technology Sydney (UTS). Prior to joining UTS, he was a JSPS Fellow and a Dean’s Scholar Fellow at Harvard School of Dental Medicine working on bone mechanobiology. Dr. Chou’s research focuses on developing different biological tools to understand cellular and disease Mechanotransduction. He developed Australia’s first cellular simulated microgravity instrument and has applied this technology together with organ-on-chip to leverage this unique condition to develop disease models, cellular regeneration and develop countermeasures against the effects of microgravity. His current focus is in understanding the dynamic mechanoenzyme signalling pathways to elucidate the role of YAP and TRPV4 in osteocyte and cancers in regulating homeostasis.
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